Comparative characteristics of gel bases for semisolid dosage forms
نویسندگان
چکیده
The article provides an overview of modern data on the main gel bases used in technology semisolid dosage forms. classes gelling substances are characterized. According to data, choice excipient must be justified from point view physicochemical properties active substance, and depends place application gel.
منابع مشابه
Semisolid Dosage Forms for Dermatological Application
ceutical dosage forms. They serve as carriers for drugs that are topically delivered by way of the skin, cornea, rectal tissue, nasal mucosa, vagina, buccal tissue, urethral membrane, and external ear lining (1). Because of their peculiar rheological behavior, semisolids can adhere to the application surface for sufficiently long periods before they are washed off. This property helps prolong d...
متن کاملIn vitro and in vivo evaluation of drug release from semisolid dosage forms.
This study presents the in vitro and in vivo testing of anti-inflammatory drug containing creams, hydrogels and organogels for dermal use. In vitro penetration studies were performed with products by measuring the diffused drug amount through synthetic membranes soaked in isopropyl myristate (IPM). Our developed preparations were investigated under in vitro conditions together with two marketed...
متن کاملDesign, Evaluation and Comparative Study of Pulsatile Release from Tablet and Capsule Dosage Forms
The objective of present research was to design, evaluate and compare drug release from two different dosage forms in pulsatile drug delivery system (DDS) for Metoprolol tartarate (MT) as tablet and capsule. Pulsatile systems are gaining a lot of interest as they deliver the drug at the right site of action at the right time and in the right amount, thus providing spatial and temporal del...
متن کاملDiffusion of preservatives from topical dosage forms: a comparative study.
A study of the diffusion of parabens from topical formulations is presented here. In particular, four different topical formulations, namely, a water-in-oil emulsion, an oil-in-water emulsion, and two hydrophilic gels (Pemulen gel and Carbopol gel) were produced, containing a mixture of three common parabens, namely, methylparaben (MP), ethylparaben (EP), and propylparaben (PP). An analytical m...
متن کاملValidated Spectrophtometric Method for Determination of Tamsulosin in Bulk and Pharmaceutical Dosage Forms
In this study a sensitive, simple and accurate spectrophotometric method was suggested for determination of tamsulosin in bulk powder and pharmaceutical dosage form based on the formation of an ion-pair complex between the drug and bromocresol green in a buffer solution at pH 3.5. The formed yellow color complex was extracted with chloroform and measured at 415 nm. The optimum reaction conditio...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BIO web of conferences
سال: 2021
ISSN: ['2273-1709', '2117-4458']
DOI: https://doi.org/10.1051/bioconf/20214003008